Obesity and stress could increase the risk of one of the most aggressive types of cancer, suggests new research.
Researchers at the University of California Los Angeles (UCLA) have found that neurotransmitters associated with stress and hormones associated with obesity activated CREB (protein binding a cyclical AMP response) that have been shown to promote growth growth from Cancer cells in the pancreas.
In the study, mice that ate a high fat diet are more likely to develop precancer lesions. When stress levels are also increased by social insulation, the lesions grew even more.
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The risk of cancer associated with stress was more pronounced in female mice.
Based on these findings, the researchers suggested to explore use Existing drugs reduce the risk of cancer associated with obesity and stress.
Obesity and stress could increase the risk of one of the most aggressive types of cancer, suggests new research. (East)
“Because β-adrenergic receptors play a crucial role in stress cancer growthUsually used beta blockers, which are medicines prescribed for high blood pressure, could be rearranged to alleviate these effects, “the public statement said.
The pancreatic cancer is one of the most deadly types in the US, with a five-year survival rate of only 13%.
One of the biggest challenges with the disease is that it is often detected at a late stage when the disease has already been advanced, according to Dr. Robert Den, a radiation oncologist, a radiation professor of oncology and the main medical officer at Alpha Tau Medical in Israel.
“Unlike some other cancers, there are no effective tools for early screening, and by the time of diagnosing the patient’s treatment, the treatment possibility of treatment is often limited,” said Den, who was not involved in the studio, for Fox News Digital.
“Unlike some other cancers, there are no effective tools for early screening, so at a time when the patient is diagnosed, treatment options are often limited.” (East)
The study enhances a strong connection between mind and body As it refers to the development of cancer, Den said.
“Stress and associated pathways can exacerbate the progression of the disease, and we know that obesity encourages certain cancers, which potentially affects the patient’s response to treatment,” he said.
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“In this case we see evidence that stress and obesity It can contribute to the exacerbation of pancreatic cancer, which has great consequences for the strategies of prevention and treatment. “
Maintenance a Heart heart diet And eating is moderately necessary, Den noted – not only because of cancer prevention, but also for overall health.
The pancreatic cancer is one of the most deadly types in the US, with a five-year survival rate of only 13%. (East)
“Exercise is especially crucial in dealing with obesity and stress,” he said. “Staying active is not only useful for physical health, but also a great way Reduce stress. “
Carefulness can also play a key role in reducing the risk of cancer, the doctor advised.
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“Spending time outdoors can also improve mental and physical well -being, so I always encourage patients to find ways to be active, connect with nature and give priority to their Overall well -being“He said.
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In a relationship pancreatic cancer Treatment, Den noted that there were some progress in chemotherapy and surgical techniques, but “there was no breakthrough”.
“Most immunotherapy, which are revolutionary in other cancers, did not show the same promise in the pancreas cancer,” he said.
“Spending outdoor time can also improve mental and physical well -being, so I always encourage patients to find ways to be active, associate with nature and prioritize their overall wellness,” said Oncologist. (East)
“The key challenge is to find ways to help patients who are not candidates for surgery, as the surgery remains the best defense line.”
Fox News Digital addressed the studio researchers for comment.
