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Drugs that reduce the risk of dementia – and others that increase it


Some medicines could have an unintentional benefit of reducing the risk of dementia.

This is according to a recent study of Cambridge and Exeter University, where researchers rated several Existing drugs To see if they can be treated with a double procedure as a dementia treatment.

The team examined data from 14 previous studies, which included more than 130 million patients and one million cases of dementia, according to a press release.

They found that several prescription classes were shown to affect the risk of dementia.

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The findings were published in Alzheimer’s and dementia: translational research and clinical intervention.

Researchers have found that several prescription classes have been shown to affect the risk of dementia. (East)

“We urgently need new treatments to slow down the progress of dementia, if not to prevent it,” said the author of the first Dr. Ben Underwood, from the Department of Psychiatry at the University of Cambridge and Cambridgeshire and Peterborough NHS Foundation Trust, in edition.

“If we can find medicines already licensed for other conditions, then we can get them in trials And – what is crucial – they may be able to make them available to patients much, much faster than we could have done for a whole new cure. “

Drugs that reduce and increase risk

Antibiotics, antiviral, anticoagulants (blood dilution) and anticonvulsants (medicines used to prevent or treat seizures) have been associated with a reduced risk of dementia, according to research.

Four vaccines – For hepatitis a, typhus, hepatitis A and typhus combination, and diphtheria – are also associated with reduced risk.

“If we can find medicines already licensed for other conditions, then we can introduce them to tests and – what is crucial – may be able to make them available to patients much, much faster than we could do for a whole new cure.” (East)

“This finding supports the hypothesis that the usual dementia may launch a virus or bacterial infectionsAnd it supports the recent interest in vaccines, such as a BCG vaccine for tuberculosis, and a reduced risk of dementia, “researchers wrote in a statement.

Anti -inflammatory drugs, such as ibuprofen, have been found to reduce the risk of dementia.

“Inflammation is increasingly seen as a significant contribution to the wide range of diseases, and its role in dementia is supported by the fact that some genes that increase the risk of dementia are part of the inflammatory paths,” the statement said.

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Some drugs are associated with increased risk of dementia including antipsychotic drugs.

There were “conflicting evidence” for other drug classes, including those indicated for blood pressure, depression and diabetes.

“Although there is no cure and available challenges to dementia, my experience emphasizes the value of personalized care,” one doctor (not in the picture) told Fox News Digital. (East)

Currently, two drugs were approved Alzheimer’s treatment In the US -U – lecammonab (leqembi) and donnemab (kisunla).

They are both monoclonal antibodies that are administered by infusions IV. They work by reducing the accumulation of amyloid plaques in the brain, but they are effective only for those with Alzheimer’s early stages and have the potential for some serious side effects, experts say.

“You should never change the medicine without discussing it first with your doctor.”

Dr. Chris Vercammen, an internal medicine doctor with a committee certificate at the University of California, San Francisco (UCSF), was not involved in the studio, but split his reaction to the findings.

“This review identifies drug classes that have an association with an increased risk of dementia,” Verscammen, which specializes in Geriatry and palliative caresaid Fox News Digital.

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“Systematic examinations offer the advantage of collecting data in multiple studies, which can provide a comprehensive understanding of the current state of knowledge on a topic.”

The study had certain restrictions, researchers acknowledged, because of the differences in the way each individual study was conducted and how data were collected.

One doctor said the findings were “convincing” and emphasized the importance of comprehensive medicines for the elderly adults at risk of dementia. (East)

Vercammen agreed that these types of examination are limited by total quality Studies available.

“Furthermore, unlike metaanalysis, they do not provide a concise size for each medicine, which makes it difficult to accurately discuss the risk.”

Despite the limitations, Vercammen said the findings are “convincing” and emphasize the importance of comprehensive medicines for the elderly at risk of dementia.

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Lourida emphasized that all medicines benefit and risk.

“You should never change the medicine without discussing it first with your doctorAnd you should talk to them if you have any doubts. “

Personalized care involves “resolving the practical needs of a person living with dementia and their carers -” other patients ” – who provide basic daily support.” (East)

Vercammen agrees that patients who consider new medicines or treatments should be consulted with their doctors.

“Although dementia does not have a cure and available drugs, they represent challenges, my experience highlights the value personalized concern“He told Fox News Digital.

For more health articles visit www.foxnews.com/health/health

“This involves the solution of practical needs of a person living with dementia and their caregivers – ‘other patients’ – who provide basic daily support. This is the essence of continuous, companious care in the absence of a cure.”



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