A new blood test that reveals has been discovered colon cancer With more than 80% accuracy – and exclude it by 90% of healthy people.
The results were presented at the American Society of Clinical Oncology Cancer in 2025, held in San Francisco late last month.
They were also published in Klinical Oncology.
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In the study, more than 27,000 adults between 45 and 85 were pulled out blood before a colonoscopy for checking Cancer signs. The participants were enrolled between May 2020 and April 2022.
It has been revealed that a new blood test detects colon cancer with more than 80% accuracy – and excludes it by 90% healthy people. (East)
Researchers tested blood samples “molecular signals of advanced colorectal cell changes” and then compared these results to colonoscopy findings.
The sensitivity of the test or its success rate in the detection of the existing colon cancer was 81.1%, the researchers revealed.
The specificity of the test, which is the share of participants who did not have colon cancer and tested negatively on it, was 90.4%.
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“Additional cancer tests are needed, which are suitable, safe and easily completed,” said Aasma Shaukat, a author of leading studies, MD, NYU Grossman Medical School, in a statement from the US Society for Clinical Oncology (ASCO).
“So far we have only had tests based on stools and colonoscopy or sigmoidoscopy (based on stool). Blood test can improve colorectal cancer The rates of the rehearsal. “
The colorectal cancer of the fourth is the most common cancer in the US and the second most important type, according to the Union of Corerektal Cancer. (East)
Pamela Kunz, MD, from the Yale Medical School, noted that the experimental blood test is a “new tool in our tool” The rehearsal option of colorectal cancer.
“The study estimated for blood rehearsal for colorectal cancer and could provide a suitable and effective option for scoop colorectal cancer in the US average risk,” Kunz, which was not involved in the studio, said the same statement for the public.
“The blood test has the potential to improve the rehearsal rate of colorectal cancer.”
Pashtoon Kasi, MD, Medical Director of Gastrointestinal Medical Oncology in City of Hope Orange in California, was not involved in the studio, but noted that these types of blood tests – also known as “liquid biopsy” – “Revolutionarize care of care about Cancer “.
“It is a simple blood test that observes various components of cancer or tumors that are spilled into the bloodstream – therefore, the term” liquid biopsy, “Fox News Digital Cassage said.
Extended screening capabilities are especially important given the trend that more people are diagnosed with colon cancer at the age of 50. (East)
Several different types of these blood tests are already breaking into a clinical practice, the doctor noted.
“Some are like this specific cancer, which will be focused on early detection of colon cancer and rectal. Other fluid tests of biopsy are what they call multicancerological tests of early detection (Mced) -What means that they can pick up more cancer in only cancer. line, “he said.
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The doctor noted that blood tests should not be used instead of colonoscopy, which remain the “golden standard” of the colon cancer.
“Colonoscopy can prevent colon cancer by discovering and removing polyps, without chance of intestinal mucosa that can become carcinogenic,” Kasi said.
“Blood tests are designed to detect cancer, not prevent it.”
If cancer is detected during blood test, it will still need to do additional tests such as colonoscopy, he added.
“Like most cancer, early detection of colon cancer usually results in Better outcomes“Kasi said.” Usually, colon cancer growing slowly and in the early stages can be asymptomatic. “
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At least the third to half of people do not get colon cancer projections, the studies show – and the hope is that the blood test can help “fill in the void”, according to the cash register.
“We know that colonoscopy usually brings unpleasant thoughts about the preparation of the bowel, the liquid diet and the shame, so it is not a surprise that the blood spin tests offer greater attraction,” he said, calling a blood test “to a potential game- change” in improvement of the rehearsal rate.
“The colorectal cancer is on a particularly steep slope – so steep that by 2030 it will be the leading cause of cancer death for young adults in the United States,” the oncologist warned. (East)
Extended screening capabilities are especially important given the trend that more people are diagnosed with colon cancer at the age of 50.
“The colorectal cancer is on a particularly steep slope – so steep that by 2030. It will be the leading cause of cancer death for young adults in the United States,” Kasi warned.
“Blood tests are designed to detect cancer, not prevent it.”
“It will be imperative expand the research In this area and for diagnostic testing available for a younger demographic group. “
The colorectal cancer of the fourth is the most common cancer in the US and the second most important type, according to the Union of Corerektal Cancer.
Blood tests should not be used instead of colonoscopy, which remain a “gold standard” of colon cancer, doctors said. (East)
Looking in advance, researchers will continue to study the long -term influence of the colorectal blood test, they noticed.
“As blood -based tests receive approval from regulatory bodies and Medicare and other payers, tests will become available for clinical use,” said the author of the leading Shaukat for Fox News Digital.
Blood based tests are opportunities for men and women between 45 and 85, which are exposed to average risk for colon cancer and for their rehearsal, the doctor noted.
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“If you have a high -risk family history or other health that increases you with the risk of colon cancer, the test is not an option,” he said. “Also, if the test is positive, a colonoscopy is required to assess colon polyp or colon cancer.”
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The researcher recommends that patients talk with their donors About the possibilities for the rehearsal of colorectal cancer, such as stool test, blood tests and colonoscopies, and choose the one that is best for them.
The study did not receive any funds, the statement said.
