Murdoch Children’s Research Institute is looking for new treatments of pediatric diseases of heart disease
The Australian Research Institute for Murdoch helps scientists use stem cell medicine and artificial intelligence to develop precise therapies for childcare diseases, leading the cause of death and disability in children.
About 260,000 children Die of heart disease around the world every year. In the US, the child is born with heart damage every 15 minutes.
“We are really interested in understanding how children develop heart disease and where we can interfere with it to stop it to progress,” said the leader of the Murdoch cardiac group for children (McRi) David Elliott.
The ladies of Elisabeth Murdoch, the mother of Fox News founder, Rupert Murdoch, helped find the Australian MCRI. The Institute is a partner with the Gladstone Institute in San Francisco for the decoding program of Broken Hearts.
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Amelia and Elijah Malllinson are two children who could benefit from this research. Brothers and sisters live in Melbourne And they have the same genetic state of the heart.
“We took her to our local emergency because she woke up, she was swollen,” said Amelia and Elijah’s mother Ebony Mallison. “We thought she was just drowsy, but it turns out she was in mind and beyond.”
Amelia was two years old when doctors discovered their condition.
Ebony Mallison, in the middle, sits with his two children, Amelia and Elijah, who live with the same genetic condition of the heart. Both of their cases are enrolled in the decoding program of broken hearts. (Fox News)
“After making a X -ray of a chest, they realized that her heart was much bigger than she had to be and realized that she was heart failure,” Mallison said.
Amelia waited almost a year to a heart transplant. After successful treatment, he lives mostly a normal life. The condition of her brother Elijah was discovered during a caution examination.
“It was a pretty shock, because we were not aware of anything that would cause him to have a heart condition. It was so much to check him just to completely exclude that there was nothing wrong with,” Mallison said. “I feel like it was scary because we could have predicted badly. But so far he has been really stable and really healthy, he still didn’t need any treatment or therapy, which is great.”
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Elliott said the goal is to be Find diagnoses and treatments Before children like Elijah ever need a transplant.
The leader of the heart disease David Elliott of the Institute for Research of Children Murdoch examines the heart image on his monitor. (Fox News)
“For many, the disease would be absolutely critical if you could correct the problem of Utero,” Elliott said. “Those who have very severe heart disease will need three operations before they are five years old. And it is very exhausting for families involved. And so, what we really want to do is really make it progress and enable these children a much more effective life.”
McRi is part of the royal children’s hospital that treats about 700 heart conditions each year. Each case is entered in the Decoding Broken Hearts program.
“We can use a special technology called reprogramming. So, we take a small blood sample of this child,” Elliott said. “From this we can create a heart cell. And in that cardiac cell, the exact replica here is here in the laboratory of a child’s heart cell.”
Researchers then create additional little heart replicas to change their function and find possible treatments for patients at Royal Children’s.
Scientists use patient’s blood samples to create small heart replicas to study, aided by artificial intelligence. (Fox News)
“We try to use all those different tools and technologies to understand how the disease develops and where we can look for new therapies using precise medicine to help children heart disease“Elliott said.
One of the latest tools with the help of a gladstone institute artificial intelligence.
“Gladstone brings expertise and computer knowledge built around the bay area to use AI to study the disease,” Elliott said. “What we all allow us is millions and millions of experiments on the computer before we introduce them to the cell, which really allows us to target and look at the ideal place to interfere, to help heal the disease.”
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Amelia and Elija also participated in the studies to further progress of treatment for conditions such as theirs.
“If it even helps one family, it pays off,” Millineson said. “Every member of the staff you contacted at the hospital and explored, everyone makes a big difference in the lives of children and all in the families of these children.”
If you want to donate or find out more about the decoding program of broken hearts you can visit Go.fox/mcri.
